Immobilized human P2RY13 fragment at 2 μg/mL (100 μL/well) can bind mouse Anti-Human P2RY13 Monoclonal Antibody (Cat. No. CABh-25323) with half maximal effective concentration (EC50) range of 5.8-23.2 ng/mL (QC tested).
Anti-Human P2RY13 Monoclonal Antibody
Product Category: All Products
Product Code: CABh-25323
Isotype: IgG1
Specificity: Human
Host Species: Mouse
Immunogen: P2RY13 N-terminus extracellular domain, the exact sequence of the immunogen is proprietary.; UniProt # Q9BPV8
Structure: 7-transmembrane protein, G protein-coupled receptor (GPCR)
Function: Possible role in hematopoiesis and the immune system
Ligand/Receptor: adenosine diphosphate (ADP)
Cell Type: Central nerve system, immune cells, hepatocytes
Molecular Family: G protein-coupled receptor
Gene ID: Q9BPV8
Product Name: P2RY13, Monoclonal Antibody
UniProt #: Q9BPV8
Predicted Molecular Weight: N/A
Protein Construct: N/A
Background and Alternate Names
Human P2Y purinoceptor 13 (P2RY13), is a 7-transmembrane G protein-coupled receptor (GPCR). It is a Class A GPCR. P2RY13 is highly expressed in the spleen and brain. P2RY13 binds adenosine diphosphate (ADP) as a ligand. P2RY13 has been found to be a possible prognostic marker for kidney renal clear cell carcinoma and lung adenocarcinoma. Human P2RY13 protein has >80% sequence homology with mouse P2RY13.