Immobilized human Claudin 9 VLP (Cat. No. CMP-24009) at 5 μg/mL (100 μL/well) can bind monoclonal anti-human Claudin 9 antibody with half maximal effective concentration (EC50) range of 18.6 to 74.4 ng/mL (QC tested).
The mean peak diameter (nm) of the CMP is 183 with a range of 165.6-202.4 with more than 95% intensity as determined by dynamic light scattering (DLS).

Human Claudin 9 Full Length Protein, Displayed on Virus-Like Particles (VLPs)

Product Category: Claudin

Product Code: CMP-24009
Expression Host: HEK293T
Verified Applications: ELISA and Western blot for Claudin 9 specific antibody binding assays.
Suggested Applications: BLI, SPR and animal immunization, RUO.
Amino Acid Range: Met1 – Val217

For Research Use Only (RUO)

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Formulation: 0.45μm filtered PBS, pH 7.4
Shipping: Frozen Dry Ice
Storage: -80’C

Datasheet

MSDS

Claudin 9 (CLDN9) is an integral membrane protein with 4 transmembrane domains. The full length human Claudin 9 protein contains 217 amino acids (Met1 – Val217; UniProt# O95484), displayed on Virus-Like Particles (VLPs), (CMP-24009) that mimics the native protein conformation on the cell surface. The Claudin 9 Virus-Like Particle (VLP,) (Claudin 9 CMP) is expressed in HEK293 cells, and has potent binding to specific antibodies.
Product Name: Claudin 9
UniProt #: O95484
Predicted Molecular Weight: N/A
Protein Construct: Claudin 9 protein contains 217 amino acids, and is displayed on Virus-Like Particles, that mimics the native protein conformation on the cell surface.

Background and Alternate Names

Claudin 9, also known as Claudin-9 and CLDN9, is an integral membrane protein with 4 transmembrane domains, two extracellular loops, one intracellular loop, and both N-terminus and C-terminus ends towards the cytosol. Human Claudin 9 is a member of the Claudin protein family, involved with tight junctions and cell-to-cell adhesion. Claudin 9 is expressed at low levels in normal tissue, but is ectopically expressed in numerous cancers. Claudin 9 is a novel prognostic biomarker for endometrial cancer and also functions as a co-receptor for Hepatitis C Virus.

Alternate Names: Claudin-9, CLDN9