Live Webinar: Uncovering New Tools to Analyze Cytokine-Receptor Interactions
How Conigen Bioscience Used Nicoya's AltoTM DIgital SPR to Characterize Novel Dimeric Receptors
Tuesday, August 5, 2025
11 AM EST / 8 AM PST
Overview
Understanding cytokine-receptor interactions is critical for advancing immunology research and therapeutic development, but capturing these interactions in a native-like state can be challenging.
In this webinar, Conigen Bioscience’s Assay Development Scientist, Dr. Alyssa Ball will share how they leveraged Nicoya’s Alto digital surface plasmon resonance (SPR) system to characterize the binding kinetics of several homo- and heterodimeric cytokine receptors, including human Type II interferon γ receptor 1 (IFNγR1) and human Type I interferon α receptor (IFNαR).
Topics covered in this webinar:
How Conigen Bioscience’s innovative soluble protein dimers enhance ligand binding sensitivity and potency of cytokine receptor proteins
Why SPR was critical for revealing nuanced differences in binding potency
How Alto digital SPR enables rapid, high-quality kinetic data for complex receptor-ligand systems
How real-time, label-free kinetic analysis combined with structural and stability characterization can accelerate the selection of functionally relevant and stable therapeutic candidates
Whether you’re working in basic immunology or drug discovery, this webinar will showcase how these innovative soluble cis-dimer proteins can significantly enhance binding potency and enable more accurate characterization of complex protein interactions.