The mean peak diameter (nm) of the CMP is 186.5 with a range of 169.4-200.3 with more than 95% intensity as determined by dynamic light scattering (DLS).
Human Claudin 3 Full Length Protein, Displayed on Virus-Like Particles (VLPs)
Claudin 3 (Claudin-3, CLDN3) is an integral membrane protein with 4 transmembrane domains. The full length human Claudin 3 protein contains 220 amino acids (Met1 – Val220; UniProt# P15551), displayed on Virus-Like Particles (VLPs), (CMP-24008) that mimics the native protein conformation on the cell surface. The Claudin 3 Virus-Like Particle (VLP), (Claudin 3 CMP) is expressed in HEK293 cells and has potent binding to specific antibodies.
Product Name: Claudin 3, VLP
UniProt #: O15551
Protein Construct: Claudin 3 protein contains 220 amino acids, and is displayed on Virus-Like Particles, that mimics the native protein conformation on the cell surface.
Background and Alternate Names
Claudin 3, also known as Claudin-3 and CLDN3, is an integral membrane protein with 4 transmembrane domains, two extracellular loops, one intracellular loop, and both N-terminus and C-terminus ends towards the cytosol. Human Claudin 3 is a member of the Claudin protein family, involved with tight junctions and cell-to-cell adhesion. Claudin 3 is expressed on intestinal epithelia cells, and associated with Williams-Beuren Syndrome and Cholesteatoma.