Detection of GLP1R in HEK293 human cell line transiently transfected with human GLP1R by Flow Cytometry. HEK293 cell line transfected with human GLP1R was stained with isotype control (black curve) or Mouse Anti-Human GLP1R Monoclonal Antibody (Cat. No. CABh-24034) (green curve) by APC-conjugated Anti-Mouse IgG Secondary Antibody.

Anti-Human GLP1R Monoclonal Antibody

Antibody

Product Code: CABh-24034
Isotype: IgG2a
Conjugate: Unconjugated
Specificity: Human glucagon-like peptide-1 receptor/GLP1R
Host Species: Mouse
Immunogen: GLP1R N-terminus, the exact sequence of the immunogen is proprietary.; UniProt # P43220
Purification: Affinity Enrichment
Verified Applications: ELISA, Flow cytometry, SPR
Recommended Usage: ELISA: starting concentration 1 µg/mL Flow cytometry: 0.2-0.8 µg/1E6 cells

For Research Use Only (RUO)

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Formulation: 0.22μm filtered PBS, pH 7.4
Shipping: Frozen Dry Ice
Storage: -80’C

Datasheet

MSDS

Structure: 7-transmembrane protein, G protein-coupled receptor (GPCR)
Function: Control of blood sugar level by enhancing insulin secretion
Ligand/Receptor: GLP-1
Cell Type: beta cells of the pancreas and on neurons of the brain
Molecular Family: G protein-coupled receptor
Gene ID: P43220
Product Name: Anti-huGLP1R
Human glucagon-like peptide-1 receptor (GLP1R), is a 7-transmembrane G protein-coupled receptor (GPCR) and is a member of the glucagon receptor family of GPCRs. It is a Class B GPCR. GLP1R is highly expressed in beta cells of the pancreas and on neurons of the brain. By binding its ligand GLP-1, it is involved in the control of blood sugar level by enhancing insulin secretion. GLP1R agonists are used as therapeutics in the treatment of type 2 diabetes and obesity. Human GLP1R protein has ~98% and ~92% sequence homology with macaque and mouse GLP1R, respectively.

Alternate Names: GLP-1-R, GLP-1R