Immobilized human GPR19 fragment at 2 μg/mL (100 μL/well) can bind Mouse Anti-Human GPR19 Monoclonal Antibody (Cat. No. CABh-24114) with half maximal effective concentration (EC50) range of 11.8-47 ng/mL (QC tested).
Anti-Human GPR19 Monoclonal Antibody
Product Category: All Products
Product Code: CABh-24114
Isotype: IgG1
Specificity: Human
Host Species: Mouse
Immunogen: GPR19 N-terminus extracellular domain, the exact sequence of the immunogen is proprietary.; UniProt # Q15760
Structure: 7-transmembrane protein, G protein-coupled receptor (GPCR)
Function: Antigen Details Structure 7-transmembrane protein, G protein-coupled receptor (GPCR) Function Regulation of circadian rhythms and energy metabolism Ligand Unknown Cell Type central nervous system Molecular Family G protein-coupled receptor Gene ID Q15760
Ligand/Receptor: Unknown
Cell Type: central nervous system
Molecular Family: G protein-coupled receptor
Gene ID: Q15760
Product Name: GPR19, Monoclonal Antibody
UniProt #: Q15760
Predicted Molecular Weight: N/A
Protein Construct: N/A
Background and Alternate Names
Human G-protein coupled receptor 19 (GPR19), is 7-transmembrane G protein-coupled receptor (GPCR). It is an orphan Class A GPCR. GPR19 is highly expressed in the central nervous system. It has been proposed that GPR19 binds adropin as a ligand. Strong GPR19 expression has been found in adenocarcinomas, typical and atypical carcinoids of the lung, and small cell lung cancer making it a possible diagnostic or therapeutic target. Human GPR19 protein has >95% and ~83% sequence homology with macaque and mouse GPR19, respectively.
Immobilized human GPR19 fragment at 2 μg/mL (100 μL/well) can bind Mouse Anti-Human GPR19 Monoclonal Antibody (Cat. No. CABh-24114) with half maximal effective concentration (EC50) range of 11.8-47 ng/mL (QC tested).