Immobilized human MC3R fragment at 2 μg/mL (100 μL/well) can bind mouse Anti-Human MC3R Monoclonal Antibody (Cat. No. CABh-25305) with half maximal effective concentration (EC50) range of 34.5-138 ng/mL (QC tested).
Anti-Human MC3R Monoclonal Antibody
Product Category: All Products
Product Code: CABh-25305
Isotype: IgG2a
Specificity: Human
Host Species: Mouse
Immunogen: MC3R N-terminus extracellular domain, the exact sequence of the immunogen is proprietary.; UniProt # P41968
Ready to buy now? Email us at sales@conigen.com and we’ll help you place your order directly.
Formulation: 0.22μm filtered PBS, pH 7.4
Shipping: Frozen Dry Ice
Storage: On receipt, store at -70 C or lower for long term storage.
This product is stable at:
-70 C for 6 months from date of receipt.
Avoid repeated freeze-thaw cycles
Structure: 7-transmembrane protein, G protein-coupled receptor (GPCR)
Function: Regulation of energy homeostasis
Ligand/Receptor: Melanocyte-stimulating hormone and adrenocorticotropic hormone
Cell Type: Predominantly central nerve system, hypothalamus
Molecular Family: G protein-coupled receptor
Gene ID: P41968
Product Name: MC3R, Monoclonal Antibody
UniProt #: P41968
Predicted Molecular Weight: N/A
Protein Construct: N/A
Background and Alternate Names
Human Melanocortin Receptor 3 (MC3R), is a 7-transmembrane G protein-coupled receptor (GPCR). MC3R is a Class A GPCR and is highly expressed in the hypothalamus. Melanocyte-stimulating hormone and adrenocorticotropic hormone are ligands for MC3R. MC3R is involved in regulation of energy homeostasis and mutations in the gene encoding MCR3 are associated with susceptibility to obesity. Human MCR3 protein has ~85-90% sequence homology with mouse MCR3.
Immobilized human MC3R fragment at 2 μg/mL (100 μL/well) can bind mouse Anti-Human MC3R Monoclonal Antibody (Cat. No. CABh-25305) with half maximal effective concentration (EC50) range of 34.5-138 ng/mL (QC tested).