Dimeric Growth Factor Receptors

Native-like Structure. Bioactive Performance. Reliable Results.

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Conigen’s recombinant growth factor receptors, including VEGFR2, FGFR1, and GHR mimic native conformations essential for signaling studies, therapeutic development, and cancer research.

Growth factor receptors are typically single-pass transmembrane proteins that bind extracellular ligands to regulate cell proliferation, migration, survival, and differentiation. Many function as homo- or heterodimers, activating intracellular pathways such as MAPK and PI3K/Akt. Dysregulation of dimerization, including ligand-independent activation or mutation-driven constitutive signaling, contributes to disease progression in cancer and developmental disorders.

Conigen’s protein dimers enable analysis of ligand binding, antibody specificity, and dimerization-state modulation for precision medicine applications.

Available Growth Factor Receptors

ProductTagSpeciesProduct CodeDetailshf:tax:product_taghf:tax:pa_species
GHR, Protein DimerHis-AviAll Species, HumanCSP-24088-03Show detailshis-avi
ObR, Protein DimerHis-AviAll Species, HumanCSP-24090Show detailshis-avi
VEGFR2, Protein DimerHis-AviAll Species, HumanCSP-25127-03Show detailshis-avi
FGFR1, Protein DimerHis-AviAll Species, HumanCSP-25129-03Show detailshis-avi
FGFR2, Protein DimerHis-AviAll Species, HumanCSP-25130-03Show detailshis-avi
FGFR3, Protein DimerHis-AviAll Species, HumanCSP-25131-03Show detailshis-avi
FGFR4, Protein DimerHis-AviAll Species, HumanCSP-25132-03Show detailshis-avi
TrkC, Protein DimerHisAll Species, HumanCSP-25169-01Show detailshis
CSF2RA, Protein DimerHis-AviAll Species, HumanCSP-25172-03Show detailshis-avi
TrkC, Protein DimerHis-AviAll Species, MouseCSP-25176-03Show detailshis-avi
CSF2R, Protein DimerHis-AviAll Species, MouseCSP-25179-03Show detailshis-avi
FGFR2, Protein DimerHisAll Species, Rhesus MacaqueCSP-25294-01Show detailshis

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We offer a wide range of recombinant conformational proteins and antibodies, and our catalog is rapidly growing. If you don’t see what you need or have a custom project in mind, send us a request!
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Spotlight: VEGFR2

Bioactive Performance
VEGFR2 is a receptor tyrosine kinase that binds VEGF-A to drive angiogenesis and tumor vascularization. Conigen’s VEGFR2 protein dimer mimics native dimerization and shows strong binding to both VEGF-A and VEGFR2-specific antibodies, supporting receptor-ligand and epitope interaction studies.

VEGFR2 His Avi ligand binding
Immobilized human VEGF-A 2 μg/mL (100 μL/well) can bind human VEGFR2 dimer protein, His-Avi tag (Cat. No. CSP-25127-03), with half maximal effective concentration (EC50) range of 38.8-155.2 μg/mL (QC tested).

These recombinant proteins offer a platform for studying receptor activation dynamics and discovering modulators of dimerization-dependent signaling in cancer and skeletal disorders