Poster: CD155 and Nectin-4 Homodimer Proteins Dramatically Enhance Binding Affinitiesto Their Receptor TIGIT

Engineered Novel CD155 and Nectin-4 Homodimer Proteins Dramatically Enhance Binding Affinities to Their Receptor TIGIT Compared to Respective Monomers Download the Poster Poster Abstract Understanding immune checkpoint receptor and ligand interactions is crucial for immuno-oncology. Nectin-4 and CD155 are part of the Nectin/Nectin-like family ligands of TIGIT (an inhibitory receptor on lymphocytes), can form homodimers […]