Poster: Cytokine receptors IFNγR1, IL10Rα and IFNαR1/2 cis-dimers significantly enhance the binding of relevant cytokines

Engineered novel cytokine receptors IFNγR1, IL10Rα and IFNαR1/2 cis-dimers significantly enhance the binding of the relevant cytokines IFNγ, IL-10 and IFNα Download the Poster Poster Abstract Cytokines initiate signaling on target cells by engaging the ectodomains (ECDs) of cell surface receptors. Cytokine receptor dimeric forms are critical for cytokine ligand binding. To mimic the dimeric […]