Dimeric Cytokine Receptors

Native-like Structure. Bioactive Performance. Reliable Results.

View All Products

Conigen’s recombinant cytokine receptors, including IFNγR1, IL10Rα, and IFNαR1/R2 mimic native quaternary structures essential for signal transduction and immune regulation. These proteins enable accurate modeling of ligand-induced dimerization and receptor activation.

Cytokine receptors translate extracellular cytokine signals into intracellular responses. Lacking intrinsic kinase activity, they rely on dimerization to activate JAK-STAT and other signaling pathways. Preformed or ligand-induced dimerization drives immune activation, proliferation, and differentiation. Structural fidelity is key to preserving binding specificity and downstream signaling efficiency.

Conigen’s dimeric cytokine receptors support high-sensitivity assays, mechanistic studies, and therapeutic development across autoimmunity, cancer, and inflammation.

Available Cytokine Receptors

ProductTagSpeciesProduct CodeDetailshf:tax:product_taghf:tax:pa_species
IFNγ R1/CD119HisHumanCSP-24015Show detailshishuman
IL-10RαHisHumanCSP-24018Show detailshishuman
IFNα-R1/R2HisHumanCSP-24025-A1B1Show detailshishuman
IL-2Rβ/γAvi, HisHumanCSP-24045-A1B5Show detailsavi hishuman
IL-15RαHis-AviHumanCSP-24064Show detailshis-avihuman
gp130His-AviHumanCSP-24081-03Show detailshis-avihuman
GCSFRHis-AviHumanCSP-24086Show detailshis-avihuman
EpoRHis-AviHumanCSP-24087Show detailshis-avihuman
PRLRHis-AviHumanCSP-24089Show detailshis-avihuman
IFNγR1HisMouseCSP-25156-01Show detailshismouse
IL-15RαHisMouseCSP-25158-01Show detailshismouse
IL-6RbHisMouseCSP-25159-01Show detailshismouse
PRLRHisMouseCSP-25160-01Show detailshismouse
CD95 (Fas)HisHumanCSP-25163-01Show detailshishuman
IL-4RαHisHumanCSP-25219-01Show detailshishuman
IL-4RαHisMouseCSP-25220-01Show detailshismouse
IL-6RαHisHumanCSP-25223-01Show detailshishuman
IL-6RαHisMouseCSP-25224-01Show detailshismouse
IL-7Rα / TSLP RHis, StrepMouseCSP-25242-A1B6Show detailshis strepmouse
IL-6Rα/gp130His, StrepHumanCSP-25249-A1B6Show detailshis strephuman
IL-10Rα/IL-10RβHis, StrepHumanCSP-25251-A1B6Show detailshis strephuman
IL6R / gp130His, StrepMouseCSP-25256-ABShow detailshis strepmouse
IFNγR1HisRhesus MacaqueCSP-25295-01Show detailshisrhesus-macaque
IL6STHisRhesus MacaqueCSP-25296-01Show detailshisrhesus-macaque

Can’t Find the Product You Need?

We offer a wide range of recombinant conformational proteins and antibodies, and our catalog is rapidly growing. If you don’t see what you need or have a custom project in mind, send us a request!
Send Your Request

Spotlight: IFNαR1/R2

IFNaR1 protein prediction
Bioactive Performance IFNαR1 and IFNαR2 form a heterodimeric receptor complex that mediates type I interferon signaling. Conigen’s IFNαR1/R2 protein heterodimer mimics native structural integrity, showing significantly enhanced binding to type I interferon compared to monomeric forms.
Human IFNαR1/R2 heterodimer, His-Tag (CSP-24025-A1B1), IFNαR1 or IFNαR2 monomer binding to Type I interferon (IFN) as measured by ELISA. IFNαR1/R2 heterodimer significantly enhances the binding to IFN compared to each monomer. The IFN (0.2 μg/ml) was coated on 96-well microtiter plates and detected by serial dilutions of IFNαR heterodimer or monomers.

This structurally optimized IFNαR1/R2 complex provides a superior tool for interferon biology studies, antiviral research, and immunotherapy development.