Dimeric Cytokine Receptors
Native-like Structure. Bioactive Performance. Reliable Results.
Conigen’s recombinant cytokine receptors, including IFNγR1, IL10Rα, and IFNαR1/R2 mimic native quaternary structures essential for signal transduction and immune regulation. These proteins enable accurate modeling of ligand-induced dimerization and receptor activation.
Cytokine receptors translate extracellular cytokine signals into intracellular responses. Lacking intrinsic kinase activity, they rely on dimerization to activate JAK-STAT and other signaling pathways. Preformed or ligand-induced dimerization drives immune activation, proliferation, and differentiation. Structural fidelity is key to preserving binding specificity and downstream signaling efficiency.
Conigen’s dimeric cytokine receptors support high-sensitivity assays, mechanistic studies, and therapeutic development across autoimmunity, cancer, and inflammation.
Available Cytokine Receptors
| Product | Tag | Species | Product Code | Product Details |
|---|---|---|---|---|
| CSP-25163-01 | ||||
| CSP-24087 | ||||
| CSP-24086 | ||||
| CSP-24025-A1B1 | ||||
| CSP-24015 | ||||
| CSP-25251-A1B6 | ||||
| CSP-24018 | ||||
| CSP-24064 | ||||
| CSP-25249-A1B6 | ||||
| CSP-25223-01 | ||||
| CSP-25219-01 | ||||
| CSP-24045-A1B5 | ||||
| CSP-24089 | ||||
| CSP-25156-01 | ||||
| CSP-25158-01 | ||||
| CSP-25295-01 | ||||
| CSP-24081-03 | ||||
| CSP-25220-01 | ||||
| CSP-25256-AB | ||||
| CSP-25224-01 | ||||
| CSP-25159-01 | ||||
| CSP-25242-A1B6 | ||||
| CSP-25160-01 | ||||
| CSP-25296-01 |
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Spotlight: IFNαR1/R2
This structurally optimized IFNαR1/R2 complex provides a superior tool for interferon biology studies, antiviral research, and immunotherapy development.